Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590449 | 1.00 | MRGPRX4 (0.49) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8593929 | 0.90 | MRGPRX4 (0.62) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8593931 | 0.90 | MRGPRX4 (0.62) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8594604 | 0.88 | TP53 (0.42) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8594603 | 0.88 | TP53 (0.42) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8592068 | 0.87 | MRGPRX4 (0.46) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8592071 | 0.87 | MRGPRX4 (0.46) | MRGPRX4MAPTTP53HTTNPC1 | |
| SCHEMBL8591904 | 0.86 | MRGPRX4 (0.47) | MRGPRX4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL8591908 | 0.86 | MRGPRX4 (0.47) | MRGPRX4MAPTNPC1RAB9AMEN1 | |
| SCHEMBL8594844 | 0.82 | FFAR1 (0.39) | MRGPRX4MAPTHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658543-B1 | PROCESS FOR PRODUCING ALPHA-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| EP-0658543-A1 | PROCESS FOR PRODUCING $g(a)-ALKOXYIMINOPHENYLACETONITRILE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |