SCHEMBL859280

SCHEMBL859280

O=C(O)Oc1cc(-c2ccccc2)n(-c2ccccc2)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPA1 P27694 3/20 0.60
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
ALDH1A1 P00352 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CACNA1G O43497 1/20 0.49
CACNA1H O95180 1/20 0.49
PTGS1 P23219 1/20 0.49
HPGD P15428 1/20 0.48
FABP4 P15090 3/20 0.47
FABP3 P05413 2/20 0.47
MDM2 Q00987 3/20 0.47
BCL2 P10415 2/20 0.47
MCL1 Q07820 2/20 0.47
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7156590 0.90 MALT1 (0.58) RPA1L3MBTL1MEN1KMT2AFABP4
SCHEMBL1110857 0.89 PPP1CA (0.57) RPA1NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL25397458 0.88 RPA1 (0.57) RPA1NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL28190691 0.87 KMT2A (0.62) RPA1NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL6679933 0.85 RPA1 (0.45) RPA1NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL5616367 0.82 FABP3 (0.53) RPA1ALDH1A1LMNAHTTCACNA1G
SCHEMBL6053761 0.82 PPP1CA (0.67) RPA1L3MBTL1MEN1KMT2AFABP4
SCHEMBL11431929 0.82 HTT (0.61) RPA1NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL3430698 0.81 PPP1CA (0.52) RPA1L3MBTL1MEN1KMT2AFABP4
SCHEMBL3430105 0.81 KMT2A (0.54) RPA1LMNAMEN1KMT2AFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2939541-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP claimed
EP-2210492-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-07-28 EP claimed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-2191716-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
EP-0558448-A1 1,5-diphenylpyrazole-3-carboxylic acid derivatives as antidotes for sulfonylurea herbicides CIBA-GEIGY AG (CH) 1993-09-01 EP claimed
EP-0268554-B1 1,5-DIPHENYL PYRAZOLE-3-CARBONIC-ACID DERIVATIVES FOR THE PROTECTION OF CULTURED PLANTS CIBA-GEIGY AG (CH) 1991-12-27 EP claimed
EP-0268554-A2 1,5-Diphenyl pyrazole-3-carbonic-acid derivatives for the protection of cultured plants CIBA-GEIGY AG (CH) 1988-05-25 EP claimed
EP-3668845-B1 HERBICIDALLY ACTIVE 3-PHENYL-5-TRIFLUORMETHYLISOXAZOLIN-5-CARBOXAMIDES OF CYCLOPENTYL CARBOXYLIC ACIDS AND ESTERS BAYER AG (DE) 2024-06-26 EP disclosed
WO-2024104956-A1 SUBSTITUTED CYCLOALKYLSULFANYLPHENYLURACILS AND THEIR SALTS, AND THEIR USE AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-05-23 WO disclosed
WO-2024104952-A1 SUBSTITUTED CYCLOPROPYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-05-23 WO disclosed
WO-2024104954-A1 SUBSTITUTED CYCLOALKYLOXYPHENYLURACILS AND SALTS THEREOF, AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-05-23 WO disclosed
EP-4367105-A1 N-(1,3,4-OXADIAZOL-2-YL)PHENYLCARBOXAMIDES AS HERBICIDES Bayer Aktiengesellschaft (DE) 2024-05-15 EP disclosed
EP-4362680-A1 HERBICIDAL COMPOSITIONS CONTAINING CINMETHYLINE AND ETHOFUMESATE Bayer Aktiengesellschaft (DE) 2024-05-08 EP disclosed
EP-2112149-A1 2-[(1H-Pyrazol-4-ylmethyl)-sulfonyl]-oxazole derivatives, 2-[(1H-pyrazol-4-ylmethyl)-sulfanyl]-oxazole derivatives and chiral 2-[(1H-pyrazol-4-ylmethyl)-sulfinyl]-oxazole derivatives, method for production of same and their use as herbicides and plant growth regulators Bayer CropScience Aktiengesellschaft (DE) 2009-10-28 EP disclosed
EP-2110019-A1 Herbicidal compounds based on N-Azinyl-N'-phenylsulfonylureas Bayer CropScience AG (DE) 2009-10-21 EP disclosed
EP-2072512-A1 Herbicide compounds based on N-Azinyl-N'-pyridylsulfonyl-ureas Bayer CropScience AG (DE) 2009-06-24 EP disclosed
EP-2064953-A1 Herbicide azole combination Bayer CropScience AG (DE) 2009-06-03 EP disclosed
EP-0268554-B1 1,5-DIPHENYL PYRAZOLE-3-CARBONIC-ACID DERIVATIVES FOR THE PROTECTION OF CULTURED PLANTS CIBA-GEIGY AG (CH) 1991-12-27 EP disclosed
EP-0268554-A2 1,5-Diphenyl pyrazole-3-carbonic-acid derivatives for the protection of cultured plants CIBA-GEIGY AG (CH) 1988-05-25 EP disclosed
EP-0268554-A2 1,5-Diphenyl pyrazole-3-carbonic-acid derivatives for the protection of cultured plants CIBA-GEIGY AG (CH) 1988-05-25 EP disclosed