Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 7/20 | 0.78 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.71 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.66 |
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056331 | 1.00 | MAP3K5 (0.78) | MAP3K5PTPN22APEX1MAPTHIF1AN | |
| SCHEMBL8594082 | 1.00 | MAP3K5 (0.78) | MAP3K5PTPN22APEX1MAPTHIF1AN | |
| SCHEMBL3893480 | 0.90 | PTPN22 (0.72) | MAP3K5PTPN22APEX1MAPTHIF1AN | |
| SCHEMBL16492645 | 0.90 | PTPN22 (0.75) | MAP3K5PTPN22APEX1MAPTHIF1AN | |
| SCHEMBL3893475 | 0.90 | PTPN22 (0.72) | MAP3K5PTPN22APEX1MAPTHIF1AN | |
| SCHEMBL13056366 | 0.90 | MAPT (0.79) | MAP3K5PTPN22APEX1MAPTHIF1AN | |
| SCHEMBL3901648 | 0.90 | MAP3K5 (0.89) | MAP3K5PTPN22MAPTHIF1ANSTAT3 | |
| SCHEMBL8593141 | 0.90 | MAP3K5 (0.89) | MAP3K5PTPN22MAPTHIF1ANSTAT3 | |
| SCHEMBL3901649 | 0.90 | MAP3K5 (0.89) | MAP3K5PTPN22MAPTHIF1ANSTAT3 | |
| SCHEMBL13056328 | 0.89 | HIF1AN (0.81) | MAP3K5PTPN22APEX1MAPTHIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998053790-A2 | COMPOUNDS THAT INHIBIT THE BINDING OF VASCULAR ENDOTHELIAL GROWTH FACTOR TO ITS RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-12-03 | — | — | WO | disclosed |