Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 19/20 | 0.97 |
| ▸ | NSD2 | O96028 | 1/20 | 0.64 |
| ▸ | MMP14 | P50281 | 1/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | CTRC | Q99895 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236789 | 0.99 | MPL (1.00) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL263650 | 0.99 | MPL (1.00) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL9271524 | 0.99 | MPL (1.00) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL29436759 | 0.99 | MPL (1.00) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL263651 | 0.99 | MPL (1.00) | MPLNSD2MMP14CASP6CTRC | |
| Water SCHEMBL23023806 | 0.97 | MPL (0.97) | MPLNSD2MMP14CASP6CTRC | |
| SCHEMBL18281628 | 0.97 | MPL (0.97) | MPLNSD2MMP14CASP6CTRC | |
| Ammonia Solution, Strong SCHEMBL18281619 | 0.97 | MPL (0.97) | MPLNSD2MMP14CASP6CTRC | |
| Ammonia Solution, Strong SCHEMBL18281621 | 0.97 | MPL (0.97) | MPLNSD2MMP14CASP6CTRC | |
| Boric Acid SCHEMBL9271214 | 0.95 | MPL (0.93) | MPLNSD2MMP14CASP6CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432642-B1 | Reagent composition, methods and kits for quantification of magnesium or calcium and magnesium | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5482866-A | ETHYLENEDIAMINETETRAACETIC ACID (EDTA), ETHYLENE GLYCOL BIS/2-AMINOETHYLETHER/-N,N,N*,N*-TETRAACETIC ACID (EGTA) AND CHLOROPHOSPHONAZO III AS CHELATING AGENTS; MEDICAL DIAGNOSIS | HOFFMANN-LA ROCHE INC. (US) | 1996-01-09 | — | — | US | disclosed |
| US-5397710-A | Fixing complexometric dye, metal mask, chelate compound alkaline buffer, and stabilizer on bibulous material covered with semipermeable membrane | DAVID DIAGNOSTICS, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0432642-A1 | A method for quantitation of calcium and magnesium | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-19 | — | — | EP | disclosed |