Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21462392 | 0.79 | KAT8 (0.56) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL28362370 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL28358737 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL1021127 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL1021979 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL9650041 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL9445790 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL1023719 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL28231260 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A | |
| SCHEMBL11587878 | 0.79 | KAT8 (0.64) | KAT8PPARABACE1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998053893-A1 | EXTRACTION AGENTS AND METHOD FOR USE THEREOF | HAMPSHIRE CHEMICAL AB (SE) | 1998-12-03 | — | — | WO | disclosed |