Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 5/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596354 | 1.00 | KMT2A (0.46) | KMT2APLGPLATLMNATDP1 | |
| SCHEMBL9431190 | 0.89 | TDP1 (0.52) | KMT2ATDP1SMN1; SMN2CKS1BSKP1 | |
| SCHEMBL8598629 | 0.84 | KMT2A (0.54) | KMT2APLGPLATLMNATDP1 | |
| SCHEMBL8598622 | 0.84 | KMT2A (0.54) | KMT2APLGPLATLMNATDP1 | |
| SCHEMBL3381027 | 0.81 | HDAC6 (0.53) | KMT2ATDP1SMN1; SMN2CKS1BSKP1 | |
| SCHEMBL3383177 | 0.81 | HDAC6 (0.49) | KMT2ATDP1SMN1; SMN2CKS1BSKP1 | |
| SCHEMBL4765060 | 0.80 | TDP1 (0.48) | KMT2ATDP1SMN1; SMN2CKS1BSKP1 | |
| SCHEMBL4380418 | 0.80 | TDP1 (0.48) | KMT2ATDP1SMN1; SMN2CKS1BSKP1 | |
| SCHEMBL2955171 | 0.80 | TDP1 (0.48) | KMT2ATDP1SMN1; SMN2CKS1BSKP1 | |
| SCHEMBL3379859 | 0.79 | HDAC6 (0.55) | KMT2ATDP1SMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |