Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 15/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551428 | 0.93 | TSHR (0.50) | TSHRHTTPPARG | |
| SCHEMBL8602443 | 0.90 | HTT (0.51) | TSHRHTTPPARGALDH1A1 | |
| SCHEMBL8595934 | 0.89 | TSHR (0.44) | TSHRPPARGALDH1A1 | |
| SCHEMBL8551630 | 0.88 | TSHR (0.43) | TSHRPPARGALDH1A1 | |
| SCHEMBL8554130 | 0.88 | TSHR (0.43) | TSHRPPARGALDH1A1 | |
| SCHEMBL8556015 | 0.86 | HTT (0.53) | TSHRHTTPPARG | |
| SCHEMBL8600322 | 0.83 | TSHR (0.42) | TSHRHTTPPARG | |
| SCHEMBL8594197 | 0.81 | TSHR (0.45) | TSHRPPARGALDH1A1 | |
| SCHEMBL8665582 | 0.81 | PPARG (0.45) | TSHRHTTPPARGALDH1A1 | |
| SCHEMBL8602959 | 0.81 | TSHR (0.44) | TSHRHTTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |