Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.68 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.57 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597259 | 0.96 | ESR1 (0.74) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8597639 | 0.92 | ESR1 (0.80) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8599829 | 0.91 | ESR1 (0.70) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8599997 | 0.91 | ESR1 (0.81) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8935070 | 0.91 | ESR1 (0.81) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8602473 | 0.90 | ESR1 (0.76) | ESR1ESR2 | |
| SCHEMBL8600306 | 0.87 | ESR1 (0.88) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8598366 | 0.86 | ESR1 (0.89) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8601304 | 0.86 | ESR1 (0.77) | ESR1ESR2ENPP1ENPP3 | |
| SCHEMBL8598353 | 0.86 | ESR1 (0.89) | ESR1ESR2ENPP1ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |