Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.40 |
| ▸ | HMGCR | P04035 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13892956 | 0.82 | TSHR (0.54) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL2595476 | 0.81 | TSHR (0.52) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL10794256 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL31509378 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL12910845 | 0.81 | TSHR (0.52) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL10403786 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL3129143 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL8411340 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL10794247 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL29357767 | 0.81 | PTPN7 (0.58) | TSHRLMNAALDH1A1PTPN7HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453127-B1 | Treatment of cataract with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5686487-A | Treatment of cataract with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0503887-B1 | Promotion of wound-healing with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0467564-B1 | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds | R TECH UENO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5346921-A | Treatment of inflammation with 15-keto-prostaglandin compounds | R-TECH UENO, LTD. (JP) | 1994-09-13 | — | — | US | disclosed |
| US-5252605-A | Promotion of wound-healing with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| US-5212324-A | TREATMENT OF CATARACT WITH 15-KETO-PROSTAGLANDIN COMPOUNDS | R.-TECH UENO LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0503887-A2 | Promotion of wound-healing with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0467564-A2 | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0453127-A2 | Treatment of cataract with 15-keto-prostaglandin compounds | R-TECH UENO LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |