SCHEMBL8597409

SCHEMBL8597409

C=CC(=O)OC(CC)OC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.39
HPGD P15428 1/20 0.38
ALDH1A1 P00352 7/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 2/20 0.33
THRB P10828 3/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPK1 P28482 1/20 0.31
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1138627 0.92 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5393796 0.86 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9155818 0.86 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27813096 0.85 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2921941 0.83 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9850076 0.83 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL315270 0.82 TSHR (0.48) TSHRALDH1A1HSD17B10CHRM2CHRM4
SCHEMBL10493403 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9155970 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5174720 0.82 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820477-A2 WATERBORNE POLYMERS WITH PENDANT CROSSLINKABLE GROUPS EASTMAN CHEMICAL COMPANY (US) 1998-01-28 EP claimed
EP-0820476-A2 WATERBORNE POLYMERS WITH PENDANT CROSSLINKABLE GROUPS EASTMAN CHEMICAL COMPANY (US) 1998-01-28 EP claimed
WO-1996032424-A2 WATERBORNE POLYMERS WITH PENDANT CROSSLINKABLE GROUPS EASTMAN CHEMICAL COMPANY (US) 1996-10-17 WO claimed
WO-1996032425-A2 WATERBORNE POLYMERS WITH PENDANT CROSSLINKABLE GROUPS EASTMAN CHEMICAL COMPANY (US) 1996-10-17 WO claimed
US-4187257-A ESTER OF POLYEPOXIDE OR POLYESTER WITH MONOESTER OF DICARBOXYLIC ACID WITH PENTAERYTHRITOL DI- OR TRIACRYLATE THE DOW CHEMICAL COMPANY (US) 1980-02-05 US claimed
CN-115244141-A Low temperature curing coating composition PPG工业俄亥俄公司 2022-10-25 CN disclosed
US-10030089-B2 Sugar free, statistical copolymers made from at least three monomers THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2018-07-24 US disclosed
EP-2981563-B1 SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS UNIV MINNESOTA (US) 2018-06-20 EP disclosed
US-9944740-B2 Sugar containing, amphiphilic copolymers REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2018-04-17 US disclosed
EP-2994493-B1 SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS UNIV MINNESOTA (US) 2017-07-19 EP disclosed
US-20160120984-A1 SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2016-05-05 US disclosed
US-20160083492-A1 SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS THE REGENTS OF THE UNIVERSITY OF MINNESOTA 2016-03-24 US disclosed
EP-2981563-A1 SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS Regents of the University of Minnesota (US) 2016-02-10 EP disclosed
WO-2014182710-A9 SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2015-11-26 WO disclosed
CN-102112094-A Primer composition for metal oxide ceramics TOKUYAMA DENTAL CORP 2011-06-29 CN disclosed
US-4269727-A AND THIOPHOSPHATES; HOMO-AND COPOLYMERS OF ACRYLIC ESTERS; FOR PLASTIC FORMULATIONS THE DOW CHEMICAL COMPANY (US) 1981-05-26 US disclosed
US-4228108-A FIREPROOFING COATINGS OF CURED POLYMER THE DOW CHEMICAL COMPANY (US) 1980-10-14 US disclosed
US-4187257-A ESTER OF POLYEPOXIDE OR POLYESTER WITH MONOESTER OF DICARBOXYLIC ACID WITH PENTAERYTHRITOL DI- OR TRIACRYLATE THE DOW CHEMICAL COMPANY (US) 1980-02-05 US disclosed
US-4054722-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-18 US disclosed
US-3933935-A THERMOSETTING THE DOW CHEMICAL COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160120984-A1 SUGAR CONTAINING, AMPHIPHILIC COPOLYMERS SLC2A3, SLC2A1, SLC2A4 TSHR 4141/4885HPGD 1489/4885ALDH1A1 1396/4885
US-20160083492-A1 SUGAR FREE, STATISTICAL COPOLYMERS MADE FROM AT LEAST THREE MONOMERS SLC2A3, SLC2A4, SLC2A1 TSHR 4395/4885HPGD 429/4885ALDH1A1 935/4885
US-10030089-B2 Sugar free, statistical copolymers made from at least three monomers SLC2A3, SLC2A4, SLC2A1 TSHR 4395/4885HPGD 429/4885ALDH1A1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.