Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859901 | 1.00 | HRH4 (0.56) | HRH4HRH3 | |
| SCHEMBL1827158 | 0.82 | HRH4 (0.57) | HRH4HRH3 | |
| SCHEMBL1827161 | 0.82 | HRH4 (0.57) | HRH4HRH3 | |
| SCHEMBL1587963 | 0.81 | HRH4 (0.81) | HRH4HRH3 | |
| SCHEMBL845994 | 0.81 | HRH4 (0.81) | HRH4HRH3 | |
| SCHEMBL19458969 | 0.81 | HRH4 (0.81) | HRH4HRH3 | |
| SCHEMBL17908157 | 0.79 | HRH4 (0.61) | HRH4HRH3 | |
| SCHEMBL17908158 | 0.79 | HRH4 (0.61) | HRH4HRH3 | |
| SCHEMBL28791452 | 0.75 | HRH4 (0.69) | HRH4HRH3 | |
| SCHEMBL17637741 | 0.75 | HRH4 (0.69) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011524363-A | — | — | 2011-09-01 | — | — | JP | claimed |
| EP-2315521-A1 | DIAMINO-PYRIDINE, PYRIMIDINE, AND PYRIDAZINE MODULATORS OF THE HISTAMINE H 4 RECEPTOR | Janssen Pharmaceutica NV (BE) | 2011-05-04 | — | — | EP | claimed |
| WO-2009152325-A1 | DIAMINO-PYRIDINE, PYRIMIDINE, AND PYRIDAZINE MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2009-12-17 | — | — | WO | claimed |