Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599068 | 1.00 | KMT2A (0.50) | KMT2APLGPLATLMNAALDH1A1 | |
| SCHEMBL4515125 | 0.89 | TDP1 (0.48) | ALDH1A1SMN1; SMN2TDP1HPGDMAPK14 | |
| SCHEMBL19116737 | 0.83 | TDP1 (0.42) | ALDH1A1SMN1; SMN2TDP1HPGDMAPK14 | |
| SCHEMBL11890389 | 0.82 | EPHX1 (0.48) | SMN1; SMN2KDM4ETDP1CYP2D6HPGD | |
| SCHEMBL8598524 | 0.82 | PLG (0.48) | KMT2APLGPLATLMNAALDH1A1 | |
| SCHEMBL8598528 | 0.82 | PLG (0.48) | KMT2APLGPLATLMNAALDH1A1 | |
| SCHEMBL9575 | 0.81 | EPHX1 (0.52) | ALDH1A1SMN1; SMN2KDM4ECYP2D6HPGD | |
| SCHEMBL8595946 | 0.79 | KMT2A (0.59) | KMT2APLGPLATLMNAALDH1A1 | |
| SCHEMBL8595943 | 0.79 | KMT2A (0.59) | KMT2APLGPLATLMNAALDH1A1 | |
| SCHEMBL916167 | 0.79 | KMT2A (0.50) | KMT2APLGPLATLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5690914-A | TRANEXAMIC ACID DERIVATIVES FOR DEPIGMENTATION | SHISEIDO CO., LTD (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0585130-A2 | External preparation for skin containing a depigmentation agent | SHISEIDO COMPANY LIMITED (JP) | 1994-03-02 | — | — | EP | disclosed |