Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553622 | 0.91 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| Hydrochloric Acid SCHEMBL8599447 | 0.89 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL1553995 | 0.87 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8601159 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8604855 | 0.85 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8598408 | 0.84 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8599076 | 0.83 | SLC22A12 (0.65) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL1554107 | 0.82 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8599802 | 0.81 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DHDAC1 | |
| SCHEMBL8602390 | 0.80 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |