SCHEMBL8599560

SCHEMBL8599560

N#CC(O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10661661 0.75
SCHEMBL14851375 0.73
SCHEMBL14851239 0.69
SCHEMBL14850837 0.69
SCHEMBL14851243 0.68
SCHEMBL29292406 0.67
SCHEMBL3499347 0.67
SCHEMBL5470241 0.67
SCHEMBL3667421 0.67
SCHEMBL1164637 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6056733-A None JP disclosed
JP-6263685-A None JP disclosed
JP-5279314-A None JP disclosed
JP-5279314-A None JP disclosed
JP-7053438-A None JP disclosed
JP-3148249-A None JP disclosed
JP-3148249-A None JP disclosed
JP-9176077-A None JP disclosed
JP-7126219-A None JP disclosed
US-20240234814-A1 COMPOSITION MEXICHEM FLUOR S.A. DE. C.V. (MX) 2024-07-11 US disclosed
JP-H09176077-A OPTICALLY INERT AND ACTIVE 1-HYDROXYL-2,2,2-TRIFLUOROETHYLE-ENDED ETHOXYALKYL KETONE AND THEIR PRODUCTION TOAGOSEI CO LTD 1997-07-08 JP disclosed
JP-H07126219-A 1-(4-BENZYLOXYBENZOYLOXY)-2,2,2-TRIFLUOROETHYL ALKYL KETONE AND ITS PRODUCTION TOAGOSEI CO LTD 1995-05-16 JP disclosed
JP-H0753438-A PRODUCTION OF 1-HYDROXY-2,2,2-TRIFLUORO-EHYLALKYL KETONE TOAGOSEI CO LTD 1995-02-28 JP disclosed
JP-H06263685-A OPTICALLY ACTIVE 1-HYDROXY-2,2,2-TRIFLUOROETHYL ALKYL KETONE AN ITS PRODUCTION TOAGOSEI CHEM IND CO LTD 1994-09-20 JP disclosed
EP-0592669-A1 OPTICALLY ACTIVE TRIFLUOROLACTIC ACID DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1994-04-20 EP disclosed
JP-H0656733-A 1-HYDROXY-2,2,2-TRIFLUOROETHYL ALKYL KETONE AND ITS PRODUCTION TOAGOSEI CHEM IND CO LTD 1994-03-01 JP disclosed
JP-H05279314-A PRODUCTION OF 2-HYDROXY-3,3,3-TRIFLUOROPROPIONITRILE TOAGOSEI CHEM IND CO LTD 1993-10-26 JP disclosed
JP-H05279314-A PRODUCTION OF 2-HYDROXY-3,3,3-TRIFLUOROPROPIONITRILE TOAGOSEI CHEM IND CO LTD 1993-10-26 JP disclosed
JP-H03148249-A PREPARATION OF 2-HYDROXY-3,3,3-TRIFLUOROPROPIONITRILE TOAGOSEI CHEM IND CO LTD 1991-06-25 JP disclosed
JP-H03148249-A PREPARATION OF 2-HYDROXY-3,3,3-TRIFLUOROPROPIONITRILE TOAGOSEI CHEM IND CO LTD 1991-06-25 JP disclosed