Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740732 | 0.86 | KMT2A (0.67) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL8947318 | 0.86 | KMT2A (0.67) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL4147862 | 0.86 | KMT2A (0.71) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL11822630 | 0.85 | KMT2A (0.65) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL7952955 | 0.84 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL16232794 | 0.84 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13922753 | 0.84 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL11373983 | 0.84 | KMT2A (0.69) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL2926341 | 0.83 | KMT2A (0.77) | KMT2AMEN1MAPK1SMN1; SMN2POLB | |
| SCHEMBL9543614 | 0.83 | MEN1 (0.67) | KMT2AMEN1MAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537786-B1 | Preparation of N-acylaminomethylphosphonic acid | SHOWA DENKO KK (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5453537-A | Method for preparing an N-phosphonomethylglycine | SHOWA DENKO K.K. (JP) | 1995-09-26 | — | — | US | disclosed |
| US-5324855-A | Mixing an N-methylolamide with phosphorus trihalide in aprotic solvent, in presence of water, heating, then adding more water, efficiency, simplification | SHOWA DENKO K.K. (JP) | 1994-06-28 | — | — | US | disclosed |
| EP-0537786-A1 | Preparation of N-acylaminomethylphosphonic acid | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1993-04-21 | — | — | EP | disclosed |