Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599848 | 1.00 | TDP1 (0.48) | TDP1GNRHRTP53ALDH1A1CHRNB2 | |
| Hydrochloric Acid SCHEMBL30596145 | 0.98 | TDP1 (0.47) | TDP1GNRHRTP53ALDH1A1CHRNB2 | |
| SCHEMBL8597654 | 0.86 | MEN1 (0.50) | TDP1GNRHRALDH1A1GAAKMT2A | |
| SCHEMBL8597658 | 0.86 | MEN1 (0.50) | TDP1GNRHRALDH1A1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL8597897 | 0.84 | MEN1 (0.49) | TDP1GNRHRALDH1A1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL8596879 | 0.84 | MEN1 (0.49) | TDP1GNRHRALDH1A1GAAKMT2A | |
| SCHEMBL8596471 | 0.84 | TDP1 (0.43) | TDP1ALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL8596475 | 0.84 | TDP1 (0.43) | TDP1ALDH1A1EPHX1KMT2AMEN1 | |
| SCHEMBL13135995 | 0.83 | TDP1 (0.48) | TDP1GNRHRTP53ALDH1A1CHRNB2 | |
| SCHEMBL8596732 | 0.83 | TDP1 (0.42) | TDP1GNRHRGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6080548-A | — | — | None | — | — | JP | disclosed |
| EP-0585130-B1 | External preparation for skin containing a depigmentation agent | SHISEIDO CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| JP-H0680548-A | DERMAL MEDICINE FOR EXTERNAL USE | SHISEIDO CO LTD | 1994-03-22 | — | — | JP | disclosed |