Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 13/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27348061 | 1.00 | HDAC2 (0.48) | HDAC2HDAC8HDAC1HDAC6HDAC3 | |
| SCHEMBL27795833 | 1.00 | HDAC2 (0.48) | HDAC2HDAC8HDAC1HDAC6HDAC3 | |
| SCHEMBL8602214 | 0.87 | — | — | |
| SCHEMBL1261313 | 0.87 | — | — | |
| SCHEMBL8600648 | 0.87 | — | — | |
| SCHEMBL31277469 | 0.84 | — | — | |
| SCHEMBL17173421 | 0.82 | — | — | |
| SCHEMBL2540688 | 0.79 | — | — | |
| SCHEMBL264926 | 0.79 | — | — | |
| SCHEMBL13450060 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733342-A | BUILDERS AND BLEACH STABILIZERS IN DETERGENTS AND CLEANING COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-31 | — | — | US | disclosed |