Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605562 | 0.94 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8553542 | 0.85 | TSHR (0.49) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8554282 | 0.84 | TSHR (0.48) | TSHRXIAPPPARG | |
| SCHEMBL8603117 | 0.83 | TSHR (0.51) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8551630 | 0.82 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8604044 | 0.82 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8553538 | 0.82 | TSHR (0.49) | TSHRPPARG | |
| SCHEMBL8602742 | 0.82 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8557746 | 0.81 | TSHR (0.45) | TSHRALDH1A1SMN1; SMN2XIAPPPARG | |
| SCHEMBL8605061 | 0.80 | TSHR (0.53) | TSHRALDH1A1SMN1; SMN2XIAPPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |