Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.46 |
| ▸ | AHCY | P23526 | 5/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580213 | 0.90 | ADORA1 (0.57) | ADORA1TRDMT1PRMT5WDR77AHCY | |
| SCHEMBL8602348 | 0.85 | TYMP (0.48) | TYMP | |
| SCHEMBL1068356 | 0.82 | ADORA1 (0.54) | ADORA1TRDMT1PRMT5WDR77AHCY | |
| SCHEMBL6394670 | 0.81 | ADORA1 (0.48) | ADORA1TRDMT1PRMT5WDR77CARM1 | |
| SCHEMBL8388204 | 0.81 | ADORA1 (0.47) | ADORA1TRDMT1AHCYCARM1TYMP | |
| SCHEMBL2111739 | 0.81 | TYMP (0.48) | ADORA1PRMT5WDR77TYMPADORA2B | |
| SCHEMBL9096320 | 0.80 | TYMP (0.56) | ADORA1PRMT5WDR77TYMPADORA2B | |
| SCHEMBL5580212 | 0.80 | ADORA1 (0.55) | ADORA1PRMT5WDR77AHCYNNMT | |
| SCHEMBL1499972 | 0.80 | ADORA1 (0.47) | ADORA1TRDMT1PRMT5WDR77AHCY | |
| SCHEMBL8433551 | 0.79 | ADORA1 (0.51) | ADORA1TRDMT1AHCYCARM1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707603-A | Pyridine complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions | NYCOMED IMAGING AS (NO) | 1998-01-13 | — | — | US | disclosed |
| EP-0691981-A1 | TUMOR TARGETING WITH L-ENANTIOMERIC OLIGONUCLEOTIDE CONJUGATES OF IMMUNOREAGENTS AND OF CHELATED RADIONUCLIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| EP-0639083-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | NYCOMED IMAGING AS (NO) | 1995-02-22 | — | — | EP | disclosed |
| WO-1994020523-A1 | TUMOR TARGETING WITH L-ENANTIOMERIC OLIGONUCLEOTIDE CONJUGATES OF IMMUNOREAGENTS AND OF CHELATED RADIONUCLIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |
| WO-1993021957-A1 | COMPLEXING AGENTS AND TARGETING IMMUNOREAGENTS | STERLING WINTHROP INC. (US) | 1993-11-11 | — | — | WO | disclosed |