Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.66 |
| ▸ | CNR1 | P21554 | 9/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601793 | 0.99 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL1554911 | 0.89 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL1553088 | 0.89 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| Hydrochloric Acid SCHEMBL8601553 | 0.88 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8602085 | 0.88 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| Hydrochloric Acid SCHEMBL8601796 | 0.86 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8603044 | 0.86 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL1553431 | 0.86 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8602314 | 0.84 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8602662 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |