SCHEMBL86018

SCHEMBL86018

C=CC(=O)Oc1ccc(Cl)c2c(=O)c3ccccc3sc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.41
MAPT P10636 4/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
HPGD P15428 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HCRTR1 O43613 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16561459 0.86 MAPT (0.38) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL8080077 0.84 MAPT (0.44) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL8078847 0.82 KMT2A (0.41) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL31120521 0.81 TYMS (0.42) TYMSMAPTNPC1RAB9AHPGD
SCHEMBL86021 0.81 HPGD (0.40) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL28027775 0.79 NPC1 (0.46) TYMSMAPTNPC1RAB9AHPGD
SCHEMBL13798431 0.78 MAPT (0.58) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL29936552 0.78 MAPT (0.58) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL16434697 0.77 MAPT (0.40) MAPTNPC1RAB9AHPGDCYP1A2
SCHEMBL30080217 0.77 PTPN1 (0.49) MAPTNPC1RAB9AHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118732123-A Optical laminate 住友化学株式会社 2024-10-01 CN disclosed
US-9670373-B2 Polymers comprising photoinitiator moieties and dye moieties LAMBSON LIMITED (GB) 2017-06-06 US disclosed
EP-2744834-B1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES LAMBSON LTD (GB) 2014-12-24 EP disclosed
US-20140316060-A1 Polymers Comprising Photoinitiator Moieties and Dye Moieties ARKEMA UK LIMITED (GB) 2014-10-23 US disclosed
EP-2744834-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES Lambson Limited (GB) 2014-06-25 EP disclosed
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
WO-2013026451-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES COLOPLAST A/S (DK) 2013-02-28 WO disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 TYMS 4732/4885MAPT 2087/4885NPC1 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.