Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370479 | 0.86 | CYP3A4 (0.39) | CYP3A4TSHRMAPK1CD44ALDH1A1 | |
| SCHEMBL11818230 | 0.86 | CYP3A4 (0.52) | CYP3A4TSHRMAPK1CD44ALDH1A1 | |
| SCHEMBL17404432 | 0.86 | CYP3A4 (0.60) | CYP3A4TSHRMAPK1CD44ALDH1A1 | |
| SCHEMBL7784067 | 0.80 | CYP3A4 (0.60) | CYP3A4TSHRMAPK1CD44ALDH1A1 | |
| SCHEMBL9737956 | 0.79 | TSHR (0.43) | CYP3A4TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL718735 | 0.77 | PTK2 (0.43) | CYP3A4TSHRMAPK1TDP1GAA | |
| SCHEMBL121858 | 0.77 | CYP3A4 (0.73) | CYP3A4TSHRMAPK1CD44ALDH1A1 | |
| SCHEMBL7682213 | 0.77 | CYP3A4 (0.37) | CYP3A4TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL29388988 | 0.77 | CYP3A4 (0.73) | CYP3A4TSHRMAPK1CD44ALDH1A1 | |
| SCHEMBL716693 | 0.74 | PTK2 (0.50) | GAAPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470467-B1 | METHINE DYES FOR COLORING PLASTICS | LANXESS DEUTSCHLAND GMBH (DE) | 2022-07-27 | — | — | EP | disclosed |
| CN-109666309-B | Methine dyes | 朗盛德国有限责任公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-109666309-A | New methine dyes | 朗盛德国有限责任公司 | 2019-04-23 | — | — | CN | disclosed |
| US-20190112486-A1 | NOVEL METHINE DYES | LANXESS DEUTSCHLAND GMBH (DE) | 2019-04-18 | — | — | US | disclosed |
| EP-3470467-A1 | NEW METHINE DYES | LANXESS Deutschland GmbH (DE) | 2019-04-17 | — | — | EP | disclosed |
| EP-3470466-A1 | NEW METHINE DYES | LANXESS Deutschland GmbH (DE) | 2019-04-17 | — | — | EP | disclosed |
| CN-101591298-A | Contain 1, hydroxamic acid derivatives, the Preparation Method And The Use of 3-two assorted five-membered ring fused benzenes | TIANJIN INST PHARM RESEARCH (CN) | 2009-12-02 | — | — | CN | disclosed |
| EP-0614930-B1 | Modified gelatin types and hydrophilic elements containing them | AGFA GEVAERT NV (BE) | 1998-02-04 | — | — | EP | disclosed |
| US-5439791-A | Having amino, sulfinic acid or thiol end groups; enhanced reactivity with vinylsulfonyl hardeners | AGFA-GEVAERT, N.V. (BE) | 1995-08-08 | — | — | US | disclosed |
| US-5418231-A | Pyrimido-benzothiazines | PFIZER INC. (US) | 1995-05-23 | — | — | US | disclosed |
| WO-1992012161-A1 | NOVEL PYRIMIDO-BENZOTHIAZINES | PFIZER INC. (US) | 1992-07-23 | — | — | WO | disclosed |
| EP-0154838-B1 | NOVEL 1,5-BENZOTHIAZEPINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4640916-A | HYPOTENSION, ANTIISCHEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0186310-A1 | 1,4-Benzothiazine Derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-07-02 | — | — | EP | disclosed |
| US-4590188-A | HYPOTENSIVES, VASODILATORS | TANABE SEIYAKU CO., LTD. (JP) | 1986-05-20 | — | — | US | disclosed |
| EP-0154838-A1 | Novel 1,5-benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1985-09-18 | — | — | EP | disclosed |
| EP-0042753-B1 | NONAPEPTIDE AND DECAPEPTIDE AGONISTS OF LUTEINIZING HORMONE RELEASING HORMONE CONTAINING HETEROCYCLIC AMINO ACID RESIDUES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM, AND THEIR PHARMACEUTICAL USE | SYNTEX (U.S.A.) INC. (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4318905-A | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues | SYNTEX (U.S.A.) INC. (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |
| EP-0039818-A1 | Substituted 2-(3H)-benzothiazolones, processes for their preparation, their utilization in the preparation of medicines and medicines containing them | Dr. Karl Thomae GmbH (DE) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190112486-A1 | NOVEL METHINE DYES | TET1, TET3, PRMT5 | CYP3A4 907/4885TSHR 3950/4885MAPK1 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.