SCHEMBL8603496

SCHEMBL8603496

CCP(c1ccccc1)c1ccccc1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43
CA14 Q9ULX7 1/20 0.43
POLB P06746 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 3/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36
ADRA2B P18089 1/20 0.36
PTGS1 P23219 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTT P42858 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPK1 P28482 1/20 0.35
IDO1 P14902 2/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932160 0.88 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL903333 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL1231880 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL30517362 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL29396701 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL25208290 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL30007746 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL10290527 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL31593 0.87 CA1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL29367537 0.87 CA1 (0.44) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108003165-A A kind of synthetic method of 5,11- dihydros -5- Phenylindoles simultaneously [3,2-b] carbazole 河南省科学院化学研究所有限公司 2018-05-08 CN claimed
CN-107868089-A A kind of synthetic method of the Phenylindole of 5,12 dihydro 5 simultaneously [3,2 a] carbazole 河南省科学院化学研究所有限公司 2018-04-03 CN claimed
CN-106317111-B A kind of method of synthesis of chiral 1,2 pairs [(2 methoxyphenyl) phenyl phosphino-] ethane 河南省科学院化学研究所有限公司 2018-01-16 CN claimed
CN-105418440-B A kind of method that the propyl alcohol of 2 amino, 2 methyl 1 is synthesized by isopropylamine 张家港吉慕特化工科技有限公司 2017-08-25 CN claimed
CN-106317111-A Chiral 1,2-bi[(2-methoxy phenyl)phenyl phosphine] ethane synthesis method 河南省科学院化学研究所有限公司 2017-01-11 CN claimed
CN-108003165-A A kind of synthetic method of 5,11- dihydros -5- Phenylindoles simultaneously [3,2-b] carbazole 河南省科学院化学研究所有限公司 2018-05-08 CN disclosed
CN-107868089-A A kind of synthetic method of the Phenylindole of 5,12 dihydro 5 simultaneously [3,2 a] carbazole 河南省科学院化学研究所有限公司 2018-04-03 CN disclosed
CN-106317111-B A kind of method of synthesis of chiral 1,2 pairs [(2 methoxyphenyl) phenyl phosphino-] ethane 河南省科学院化学研究所有限公司 2018-01-16 CN disclosed
CN-106317111-B A kind of method of synthesis of chiral 1,2 pairs [(2 methoxyphenyl) phenyl phosphino-] ethane 河南省科学院化学研究所有限公司 2018-01-16 CN disclosed
CN-106317111-B A kind of method of synthesis of chiral 1,2 pairs [(2 methoxyphenyl) phenyl phosphino-] ethane 河南省科学院化学研究所有限公司 2018-01-16 CN disclosed
CN-105418440-B A kind of method that the propyl alcohol of 2 amino, 2 methyl 1 is synthesized by isopropylamine 张家港吉慕特化工科技有限公司 2017-08-25 CN disclosed
CN-107074675-A Preparation method of chiral 2- [ 1-cyclopropylethyl ] -6-isopropyl-phenol 四川海思科制药有限公司 2017-08-18 CN disclosed
CN-102858788-A Ruthenium complex and method for preparing optically active alcohol compound TAKASAGO PERFUMERY CO LTD 2013-01-02 CN disclosed
CN-1926083-B Manufacturing method of optical activity alcohol KANTO KAGAKU 2010-12-08 CN disclosed
CN-101676294-A Method for producing ruthenium complex TAKASAGO PERFUMERY CO LTD 2010-03-24 CN disclosed
CN-101495491-A Process for producing optically active aminophosphinylbutanoic acid MEIJI SEIKA KAISHA (JP) 2009-07-29 CN disclosed
CN-1926083-A Manufacturing method of optical activity alcohol NAGOYA IND SCIENCE RES INST (JP) 2007-03-07 CN disclosed
CN-1187830-A Catalyst composition and process for preparation of copolymers of carbon monoxide and olefinically unsaturated compound SHELL INT RESEARCH (NL) 1998-07-15 CN disclosed
US-5780692-A CATALYTIC ASYMMETRIC HYDROGENATION OF A BENZOPHENONE; SIMPLIFICATION TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-07-14 US disclosed
US-5614641-A USING A PHOSPHINO-CONTAINING RUTHENIUM COMPLEX AS CATALYST ELF AQUITAINE (FR) 1997-03-25 US disclosed