Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 11/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321529 | 0.83 | TRPV1 (0.52) | NAAA | |
| SCHEMBL27585361 | 0.81 | TRPV1 (0.58) | NAAA | |
| SCHEMBL29315201 | 0.80 | MME (0.41) | S1PR1S1PR3MMEEPHX1EPHX2 | |
| SCHEMBL9343156 | 0.79 | S1PR1 (0.44) | S1PR1S1PR3EPHX1ALOX5EPHX2 | |
| SCHEMBL12901103 | 0.77 | EPHX1 (0.50) | S1PR1S1PR3EPHX1EPHX2NAAA | |
| SCHEMBL2864322 | 0.77 | MME (0.40) | S1PR1S1PR3MMEEPHX1ALOX5 | |
| SCHEMBL2863809 | 0.77 | MME (0.38) | S1PR1S1PR3MMEEPHX1ALOX5 | |
| SCHEMBL2855042 | 0.76 | MME (0.40) | S1PR1S1PR3MMEEPHX1ALOX5 | |
| SCHEMBL2860555 | 0.76 | S1PR1 (0.39) | S1PR1S1PR3MMEEPHX1ALOX5 | |
| SCHEMBL10501536 | 0.75 | CNR2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767113-A | Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1996035426-A1 | COMPOUNDS USEFUL FOR CONCURRENTLY ACTIVATING GLUCOCORTICOID-INDUCED RESPONSE AND REDUCING MULTIDRUG RESISTANCE | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-11-14 | — | — | WO | disclosed |