Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 5/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054408 | 0.94 | TDP1 (0.42) | TDP1FFAR3ALDH1A1LCKFYN | |
| Acetone SCHEMBL10428691 | 0.94 | TDP1 (0.42) | TDP1FFAR3ALDH1A1LCKFYN | |
| SCHEMBL17865 | 0.94 | — | — | |
| SCHEMBL156659 | 0.94 | FFAR3 (0.47) | TDP1FFAR3ALDH1A1TET2TET3 | |
| Methacrylic Acid SCHEMBL11665801 | 0.92 | TDP1 (0.40) | TDP1FFAR3ALDH1A1LCKFYN | |
| Methacrylic Acid SCHEMBL121821 | 0.92 | TDP1 (0.40) | TDP1FFAR3ALDH1A1LCKFYN | |
| Methacrylic Acid SCHEMBL11241511 | 0.92 | TDP1 (0.40) | TDP1FFAR3ALDH1A1LCKFYN | |
| Methacrylic Acid SCHEMBL4484002 | 0.92 | TDP1 (0.40) | TDP1FFAR3ALDH1A1LCKFYN | |
| Oxalic Acid SCHEMBL7521918 | 0.91 | FFAR3 (0.44) | TDP1FFAR3ALDH1A1TET2TET3 | |
| Ammonia Solution, Strong SCHEMBL93844 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100590225-C | Method for preparing and using silicate systems to treat electrically conductive surfaces and products obtained therefrom | ELISHA HOLDING LLC | 2010-02-17 | — | — | CN | disclosed |
| CN-1735715-A | Method for preparing and using silicate systems to treat electrically conductive surfaces and products obtained therefrom | ELISHA HOLDING LLC (US) | 2006-02-15 | — | — | CN | disclosed |
| US-5770303-A | POLYVINYL ESTER FIRST STAGE LATEX PARTICLES IN SEPARATE PHASE SECOND STAGE LATEX COMPRISING UNSATURATED ACID AND VINYL AROMATIC COMPOUND AND/OR CONJUGATED DIENE; BINDERS, PAPER COATING, NONAGGLOMERATING | GENCORP INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5286624-A | Indicator layer contains polyvinyl alkyl ether as binder polymer | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| US-4629680-A | ACRYLATE-UNSATURATED CARBOXYLIC ACID COPOLYMER BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1986-12-16 | — | — | US | disclosed |