Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154490 | 1.00 | CA1 (0.52) | CA1CA2CA9BCHEPOLB | |
| SCHEMBL7151066 | 1.00 | CA1 (0.52) | CA1CA2CA9BCHEPOLB | |
| SCHEMBL7150003 | 1.00 | CA1 (0.52) | CA1CA2CA9BCHEPOLB | |
| SCHEMBL7150000 | 1.00 | CA1 (0.52) | CA1CA2CA9BCHEPOLB | |
| SCHEMBL7151320 | 0.84 | PTPN1 (0.52) | BCHESLC6A2 | |
| SCHEMBL7149861 | 0.84 | PTPN1 (0.52) | BCHESLC6A2 | |
| SCHEMBL7149867 | 0.84 | PTPN1 (0.52) | BCHESLC6A2 | |
| SCHEMBL7151321 | 0.84 | PTPN1 (0.52) | BCHESLC6A2 | |
| SCHEMBL22965651 | 0.81 | BCHE (0.48) | BCHEPOLBGAAALDH1A1METAP2 | |
| SCHEMBL10791199 | 0.81 | BCHE (0.46) | CA1CA2CA9BCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773239-A | ENZYME INHIBITORS FORMED BY MULTISTAGE REACTION FOR USE AS PRODRUGS | MOUNT SINAI HOSPITAL CORPORATION. (CA) | 1998-06-30 | — | — | US | disclosed |