Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.79 |
| ▸ | PTGFR | P43088 | 14/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Latanoprost Acid SCHEMBL18651274 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL1514745 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL19847192 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL1313162 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL12458743 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL1313159 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL12608975 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL12087458 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL21087135 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 | |
| Latanoprost Acid SCHEMBL12076372 | 0.88 | SLCO2A1 (1.00) | SLCO2A1PTGFRKDM4EMEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825980-A1 | CYCLOPENTANE HEPTAN(ENE)OIC ACID, 2-HETEROARYLAKENYL DERIVATIVES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF OCULAR HYPERTENSION | Allergan (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036599-A1 | CYCLOPENTANE HEPTAN(ENE)OIC ACID, 2-HETEROARYLALKENYL DERIVATIVES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF OCULAR HYPERTENSION | ALLERGAN (US) | 1996-11-21 | — | — | WO | disclosed |