SCHEMBL8604284

SCHEMBL8604284

CCCCOC(=O)Nc1ccc(O)c(C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.59
NPC1 O15118 9/20 0.59
SMN1; SMN2 Q16637 8/20 0.59
HPGD P15428 7/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
LMNA P02545 1/20 0.56
KDM4E B2RXH2 5/20 0.56
MAPT P10636 5/20 0.56
ALDH1A1 P00352 5/20 0.56
KDM4C Q9H3R0 2/20 0.56
MCL1 Q07820 2/20 0.56
CASP1 P29466 1/20 0.56
MAPK1 P28482 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KMT2A Q03164 4/20 0.55
HSD17B10 Q99714 2/20 0.55
MEN1 O00255 2/20 0.55
POLB P06746 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655203 0.96 KDM4E (0.54) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592318 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1593214 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592302 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592312 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592859 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL8658138 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592339 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592303 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2
SCHEMBL1592911 0.95 KDM4E (0.53) RAB9ANPC1SMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630758-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-10-07 EP disclosed
EP-0675002-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1998-02-25 EP disclosed
US-5476957-A Dye for heat sensitive recording MITSUI TOATSU CHEMICALS, INC. (JP) 1995-12-19 US disclosed
US-5466655-A STORAGE STABILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1995-11-14 US disclosed
EP-0675002-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1995-10-04 EP disclosed
EP-0630758-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1994-12-28 EP disclosed