SCHEMBL8606261

SCHEMBL8606261

C[S+]([O-])c1c(C(=O)C(C#N)C(=O)C2CC2)ccc(Cl)c1F

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608883 0.89
SCHEMBL8609762 0.82
SCHEMBL8608435 0.80 GAA (0.31)
SCHEMBL8609420 0.80 USP2 (0.31) USP2HPGD
SCHEMBL8605815 0.79 USP2 (0.30) USP2HPGD
SCHEMBL8953184 0.76 NOTUM (0.36)
SCHEMBL8043259 0.72
SCHEMBL8609547 0.72 HPGD (0.30) HPGD
SCHEMBL8606438 0.71 SLC6A2 (0.32)
SCHEMBL29557984 0.71 SLC6A2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5804532-A REACTING A BENZOYL ISOXAZOLE WITH A BASE RHONE-POULENC AGRICULTURE LIMITED (GB) 1998-09-08 US disclosed