SCHEMBL8606709

SCHEMBL8606709

CC(N)CNC(=O)CCc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.42
ERCC1 P07992 1/20 0.40
ERCC4 Q92889 1/20 0.40
MAOB P27338 2/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
HSD17B10 Q99714 1/20 0.38
TRPV1 Q8NER1 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
AGTR1 P30556 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NR1H2 P55055 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608144 0.87 HPGD (0.43) ERCC1ERCC4TRPV1
SCHEMBL8606890 0.86 GAA (0.66) GAAKMT2AMEN1MAOBMAOA
SCHEMBL8606268 0.84 KMT2A (0.47) GAAKMT2AMEN1
SCHEMBL8605886 0.82 GAA (0.56) GAAKMT2AMEN1ERCC1ERCC4
SCHEMBL9677227 0.82 KMT2A (0.59) GAAKMT2AMEN1MAOBMAOA
SCHEMBL8634577 0.81 GAA (0.56) GAAKMT2AMEN1MAOBMAOA
SCHEMBL8340607 0.81 GAA (0.71) GAAKMT2AMEN1ERCC1ERCC4
SCHEMBL4600026 0.81 GAA (0.54) GAAKMT2AMEN1MAOBMAOA
SCHEMBL7944852 0.81 KMT2A (0.58) GAAKMT2AMEN1ERCC1ERCC4
SCHEMBL924084 0.81 KMT2A (0.58) GAAKMT2AMEN1MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed