Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26086370 | 0.91 | CHRM2 (0.50) | GAAMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL26087454 | 0.83 | SMPD1 (0.52) | MEN1MAPTKMT2ACHRM2GRIN1 | |
| SCHEMBL30395604 | 0.80 | CYP1A2 (0.47) | MEN1ALDH1A1KMT2ACHRM2GRIN1 | |
| SCHEMBL26086346 | 0.80 | CYP1A2 (0.47) | MEN1ALDH1A1KMT2ACHRM2GRIN1 | |
| SCHEMBL26411467 | 0.78 | HTR2A (0.41) | GAAHTR2AHTR2CMEN1MAPT | |
| SCHEMBL8608362 | 0.75 | GAA (0.45) | GAAERN1HTR2AHTR2CMEN1 | |
| SCHEMBL8608371 | 0.75 | GAA (0.45) | GAAERN1HTR2AHTR2CMEN1 | |
| SCHEMBL14417263 | 0.74 | GAA (0.60) | GAAERN1MEN1ALDH1A1MAPT | |
| SCHEMBL293625 | 0.74 | GAA (0.56) | GAAERN1MEN1ALDH1A1MAPT | |
| SCHEMBL21411132 | 0.72 | ERN1 (0.58) | GAAERN1MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831806-A1 | MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF | WASHINGTON UNIVERSITY (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040108-A1 | MULTIDENTATE METAL COMPLEXES AND METHODS OF MAKING AND USING THEREOF | WASHINGTON UNIVERSITY (US) | 1996-12-19 | — | — | WO | disclosed |