Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29071418 | 0.85 | FFAR1 (0.49) | FFAR1DGAT1USP30CA1CA2 | |
| SCHEMBL1269464 | 0.84 | FFAR1 (0.47) | FFAR1DGAT1USP30 | |
| SCHEMBL1650157 | 0.82 | FFAR1 (0.50) | FFAR1DGAT1IRAK4USP30CA1 | |
| SCHEMBL141413 | 0.81 | FFAR1 (0.52) | FFAR1DGAT1USP30CA1CA2 | |
| SCHEMBL14654744 | 0.80 | FFAR1 (0.52) | FFAR1DGAT1IRAK4USP30CA1 | |
| SCHEMBL680013 | 0.80 | FFAR1 (0.52) | FFAR1DGAT1IRAK4CA1CA2 | |
| SCHEMBL29108989 | 0.79 | FFAR1 (0.51) | FFAR1DGAT1IRAK4CA1CA2 | |
| SCHEMBL381301 | 0.78 | FFAR1 (0.46) | FFAR1DGAT1USP30UCHL1 | |
| SCHEMBL17165884 | 0.77 | FFAR1 (0.45) | FFAR1DGAT1UCHL1 | |
| SCHEMBL13412136 | 0.76 | FFAR1 (0.49) | FFAR1DGAT1IRAK4USP30CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432771-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135360-A1 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |