SCHEMBL8610155

SCHEMBL8610155

COc1c(-c2cccc(CCO)c2)cccc1[C@H]1O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SELP P16109 7/20 0.44
SELL P14151 2/20 0.43
SLC5A2 P31639 7/20 0.38
HTR7 P34969 3/20 0.38
SLC5A1 P13866 2/20 0.36
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
SELPLG Q14242 1/20 0.34
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588806 0.85 SELP (0.62) SELPSELLSLC5A2SELPLG
SCHEMBL8586082 0.78 SELP (0.61) SELPSELLSLC5A2SLC5A1SELPLG
SCHEMBL8611776 0.76 SELP (0.41) SELPSELLSLC5A2SLC5A1
SCHEMBL8585085 0.76 SELP (0.71) SELPSELLSLC5A2SLC5A1
SCHEMBL8584062 0.76 SELP (0.71) SELPSELLSLC5A2SLC5A1
SCHEMBL8611563 0.69 SELP (0.38) SELPSELLSLC5A2SLC5A1
SCHEMBL8587086 0.68 SELP (0.39) SELPSELLSLC5A2SLC5A1PDCD1
SCHEMBL8585721 0.68 SELP (0.62) SELPSELLSLC5A2SLC5A1
SCHEMBL9146235 0.65 SELP (0.63) SELPSLC5A2SELPLG
SCHEMBL9146227 0.65 SELP (0.63) SELPSLC5A2SELPLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998031697-A1 ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF SANKYO COMPANY, LIMITED (JP) 1998-07-23 WO disclosed