Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608513 | 1.00 | ADORA2A (0.80) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8609666 | 0.97 | ADORA2A (0.83) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL9271423 | 0.95 | ADORA2A (0.82) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8325227 | 0.92 | ADORA2A (0.87) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8436686 | 0.91 | ADORA2A (0.85) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL13863054 | 0.90 | ADORA2A (0.74) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL13863065 | 0.90 | ADORA2A (0.74) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8610447 | 0.89 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8606911 | 0.89 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8609426 | 0.89 | ADORA2A (1.00) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680488-B1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LTD (GB) | 1998-04-08 | — | — | EP | disclosed |
| EP-0680488-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017090-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |