Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 13/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610184 | 1.00 | TYMP (0.43) | TYMPADORA3ADORA2AADORA1NT5E | |
| SCHEMBL8611906 | 0.89 | NT5E (0.43) | TYMPNT5E | |
| SCHEMBL8611900 | 0.89 | NT5E (0.43) | TYMPNT5E | |
| SCHEMBL8609630 | 0.83 | TYMP (0.43) | TYMPADORA1NT5E | |
| SCHEMBL8609626 | 0.83 | TYMP (0.43) | TYMPADORA1NT5E | |
| SCHEMBL8611071 | 0.82 | TYMP (0.49) | TYMPADORA1 | |
| SCHEMBL8614262 | 0.81 | TYMP (0.49) | TYMPADORA1 | |
| SCHEMBL8610245 | 0.81 | TYMP (0.47) | TYMPADORA1 | |
| SCHEMBL8614306 | 0.80 | TYMP (0.47) | TYMPNT5E | |
| SCHEMBL8610449 | 0.79 | TYMP (0.47) | TYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |