Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 9/20 | 0.75 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.75 |
| ▸ | GRIK5 | Q16478 | 8/20 | 0.75 |
| ▸ | GRIK3 | Q13003 | 8/20 | 0.75 |
| ▸ | GRIA1 | P42261 | 7/20 | 0.75 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.75 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.75 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.75 |
| ▸ | GRIK4 | Q16099 | 5/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611573 | 0.87 | GRIK1 (0.72) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8611517 | 0.86 | GRIK1 (1.00) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8609541 | 0.85 | GRIK1 (0.74) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8609604 | 0.81 | GRIK1 (0.78) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8673956 | 0.80 | GRIA1 (1.00) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8610087 | 0.79 | GRIK1 (0.82) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8613051 | 0.76 | GRIK1 (0.71) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL2053498 | 0.75 | GRIA1 (1.00) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8609255 | 0.75 | GRIK1 (0.69) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| Zonampanel SCHEMBL29379917 | 0.74 | SLC22A6 (1.00) | GRIK1GRIK2GRIK5GRIK3GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |