Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CDC25B | P30305 | 4/20 | 0.41 |
| ▸ | CDC25A | P30304 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phentydrone SCHEMBL10359108 | 0.84 | MEN1 (0.44) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| Phentydrone SCHEMBL875187 | 0.84 | MEN1 (0.57) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| Phentydrone SCHEMBL9628384 | 0.82 | MEN1 (0.50) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| Anthraquinone SCHEMBL11352939 | 0.82 | MEN1 (0.60) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL545308 | 0.80 | MEN1 (0.55) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL29519720 | 0.80 | MEN1 (0.55) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL28215631 | 0.80 | MEN1 (0.55) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL10697311 | 0.78 | MEN1 (0.52) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL29080974 | 0.78 | CDC25B (0.52) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA | |
| SCHEMBL10697306 | 0.78 | MEN1 (0.52) | ALDH1A1RAB9AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770732-A | STABLE NON-PEPTIDAL COMPOUNDS WHICH CAN INHIBIT THE CHEMICAL ACTIVITY OF PEPTIDES AND ENZYMES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0776326-A4 | PYRROLINONE-BASED PEPTIDOMIMETICS | UNIV PENNSYLVANIA (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0776326-A1 | PYRROLINONE-BASED PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-06-04 | — | — | EP | disclosed |