Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.82 |
| ▸ | TYMP | P19971 | 9/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | DPP4 | P27487 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.64 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.64 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.64 |
| ▸ | GAPDH | P04406 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | STAT6 | P42226 | 1/20 | 0.64 |
| ▸ | PI4KA | P42356 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.64 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610903 | 1.00 | ADORA1 (0.82) | ADORA1TYMPSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL31484253 | 1.00 | ADORA1 (0.82) | ADORA1TYMPSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL16715145 | 0.93 | ADORA1 (0.75) | ADORA1TYMPSMN1; SMN2DNPH1PRKAB2 | |
| SCHEMBL1068571 | 0.93 | ADORA1 (0.75) | ADORA1TYMPSMN1; SMN2DNPH1PRKAB2 | |
| SCHEMBL8359104 | 0.93 | ADORA1 (0.75) | ADORA1TYMPSMN1; SMN2DNPH1PRKAB2 | |
| SCHEMBL15993919 | 0.93 | ADORA1 (0.75) | ADORA1TYMPSMN1; SMN2DNPH1PRKAB2 | |
| SCHEMBL6271785 | 0.92 | NT5E (0.73) | ADORA1TYMP | |
| SCHEMBL6271787 | 0.92 | NT5E (0.73) | ADORA1TYMP | |
| SCHEMBL3318862 | 0.92 | NT5E (0.73) | ADORA1TYMP | |
| SCHEMBL5859561 | 0.91 | ADORA1 (0.72) | ADORA1TYMPSMN1; SMN2DNPH1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5525720-A | Synthesis of 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosyl purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |