Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611340 | 1.00 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8614231 | 0.81 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8613221 | 0.81 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8614228 | 0.81 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8613225 | 0.81 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL9540616 | 0.80 | SRD5A2 (0.73) | SRD5A2SRD5A1 | |
| SCHEMBL8611392 | 0.80 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8611390 | 0.80 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8610450 | 0.78 | SRD5A2 (1.00) | SRD5A2SRD5A1 | |
| SCHEMBL8610446 | 0.78 | SRD5A2 (1.00) | SRD5A2SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641356-B1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC (US) | 1998-04-22 | — | — | EP | claimed |
| WO-1993013124-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO INC. (US) | 1993-07-08 | — | — | WO | claimed |
| EP-0641356-B1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC (US) | 1998-04-22 | — | — | EP | disclosed |
| US-5543406-A | TREATING ANDROGEN RESPONSIVE OR MEDIATED DISEASE | GLAXO WELLCOME, INC. (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0641356-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993013124-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO INC. (US) | 1993-07-08 | — | — | WO | disclosed |