SCHEMBL861171

SCHEMBL861171

O=C1C#CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3439225 0.55
SCHEMBL10426602 0.53
SCHEMBL1431864 0.53
SCHEMBL232122 0.53
SCHEMBL3572806 0.52
SCHEMBL119955 0.46
SCHEMBL7981543 0.46
SCHEMBL7645220 0.43 TRIM24 (0.64)
SCHEMBL3115436 0.43
SCHEMBL3118747 0.43

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970146-B1 ACYLAMINOCYCLOALKYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF DOPAMINE D3 RECEPTOR ABBVIE DEUTSCHLAND (DE) 2017-11-01 EP claimed
EP-2252612-B1 HETEROCYCLIC COMPOUNDS AND COMPOSITIONS AS C-KIT AND PDGFR KINASE INHIBITORS IRM LLC (BM) 2012-03-28 EP claimed
EP-1761542-B1 OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS HOFFMANN LA ROCHE (CH) 2008-01-02 EP claimed
EP-0793499-B1 METHOD AND COMPOSITION FOR REDUCING TUMOR DEVELOPMENT WITH A COMBINATION OF A TAXANE COMPOUND AND A TELLURIUM AND/OR SELENIUM COMPOUND BAKER NORTON PHARMA (US) 2005-10-19 EP claimed