⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101400 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL29471655 | 0.83 | — | — | |
| SCHEMBL4022349 | 0.83 | SLC6A2 (0.35) | — | |
| SCHEMBL670611 | 0.79 | — | — | |
| SCHEMBL4911622 | 0.79 | — | — | |
| SCHEMBL15424763 | 0.79 | — | — | |
| SCHEMBL19125195 | 0.79 | SRC (0.33) | — | |
| SCHEMBL5025313 | 0.75 | — | — | |
| SCHEMBL14645942 | 0.74 | MEN1 (0.35) | — | |
| SCHEMBL16504608 | 0.74 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | claimed |
| US-20230357578-A1 | AIRTIGHT FILM WITH CERAMIC SEALING LAYER AND POLYMER SEALING LAYER | Quantum MicroMaterials, Inc. | 2023-11-09 | — | — | US | claimed |
| US-11524968-B2 | Heterocyclic compound as a protein kinase inhibitor | HK INNO.N CORPORATION (KR) | 2022-12-13 | — | — | US | claimed |
| CN-111603478-B | Composition for nasal cavity | 华熙生物科技股份有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-109212107-A | A kind of non-invasive screening system of pyridoxine dependency epilepsy | 北京大学第医院 | 2019-01-15 | — | — | CN | claimed |
| US-9828369-B2 | Isoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2 | MERCK SHARPE & DOHME CORP. (US) | 2017-11-28 | — | — | US | claimed |
| US-20170275274-A1 | ISOQUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME CORP. (US) | 2017-09-28 | — | — | US | claimed |
| US-12435066-B2 | Substituted tricyclic compounds | LUPIN LIMITED (IN) | 2025-10-07 | — | — | US | disclosed |
| US-20250163048-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4551556-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | Vividion Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025092818-A1 | PYRIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2025-05-08 | — | — | WO | disclosed |
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| US-12240836-B2 | Compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | DONG-A ST CO., LTD. (KR) | 2025-03-04 | — | — | US | disclosed |
| WO-2003004027-A1 | SUBSTITUTED ANILINIC PIPERIDINES AS MCH SELECTIVE ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2003-01-16 | — | — | WO | disclosed |
| US-5622681-A | ION EXCHANGING HEAT STABLE SALT ANION WITH BASIC DIALYZING SOLUTION TO CONVERT TO HEAT REGENERABLE AMINE ABSORBENT; DONNAN EXCLUSION PRINCIPLES | THE DOW CHEMICAL COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| EP-0471592-B1 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | DOW CHEMICAL CO (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5236678-A | Process for absorption of sulfur compounds from fluids using piperidines | THE DOW CHEMICAL COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0552360-A1 | A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1993003825-A1 | A COMPOSITION AND METHOD FOR SIMULTANEOUS ABSORPTION OF SULFUR DIOXIDE AND NITRIC OXIDE | THE DOW CHEMICAL COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
| EP-0471592-A2 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | THE DOW CHEMICAL COMPANY (US) | 1992-02-19 | — | — | EP | disclosed |