Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 9/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.55 |
| ▸ | GRIK5 | Q16478 | 7/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 7/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.55 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612849 | 0.89 | GRIA1 (0.58) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8612853 | 0.89 | GRIA1 (0.58) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8611636 | 0.86 | GRIA1 (0.56) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8681277 | 0.85 | GRIA1 (0.76) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8611264 | 0.85 | GRIK1 (0.55) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8610384 | 0.83 | GRIA1 (0.79) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8609423 | 0.79 | GRIA1 (0.65) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8611278 | 0.77 | GRIK1 (0.47) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8608799 | 0.75 | GRIK1 (0.46) | GRIK1GRIK2GRIK5GRIK3GRIA1 | |
| SCHEMBL8290910 | 0.75 | GRIK1 (0.59) | GRIK1GRIK2GRIK5GRIK3GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |