Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686743 | 0.76 | CYSLTR2 (0.51) | ACACBACACACYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL24675623 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4ELMNASMN1; SMN2CYSLTR2 | |
| SCHEMBL17138208 | 0.69 | PRSS1 (0.46) | ALDH1A1KDM4EHPGD | |
| SCHEMBL31267654 | 0.68 | KDM4E (0.57) | ALDH1A1KDM4ELMNASMN1; SMN2HPGD | |
| SCHEMBL29675897 | 0.68 | ACACB (0.60) | ACACBACACAMTNR1AMTNR1B | |
| SCHEMBL3186986 | 0.67 | KMT2A (0.61) | ALDH1A1KDM4E | |
| SCHEMBL17138168 | 0.67 | KCNA3 (0.46) | ALDH1A1KDM4EHPGD | |
| SCHEMBL3186894 | 0.66 | KMT2A (0.63) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL201096 | 0.65 | PRSS1 (0.56) | ALDH1A1 | |
| SCHEMBL201121 | 0.65 | PRSS1 (0.56) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |