Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 11/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 3/20 | 0.49 |
| ▸ | NPEPPS | P55786 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610268 | 0.93 | TYMP (0.63) | TYMPADORA1ANPEPNPEPPSADORA2A | |
| SCHEMBL8612735 | 0.88 | TYMP (0.54) | TYMPADORA1ANPEPNPEPPS | |
| SCHEMBL8612740 | 0.88 | TYMP (0.54) | TYMPADORA1ANPEPNPEPPS | |
| SCHEMBL8611837 | 0.88 | TYMP (0.67) | TYMPADORA1 | |
| SCHEMBL8612918 | 0.87 | TYMP (0.52) | TYMPADORA1 | |
| SCHEMBL8613000 | 0.87 | TYMP (0.83) | TYMPADORA1 | |
| SCHEMBL8612341 | 0.86 | TYMP (0.63) | TYMPADORA1 | |
| SCHEMBL8614133 | 0.85 | TYMP (0.64) | TYMPADORA1 | |
| SCHEMBL18797886 | 0.84 | TYMP (0.62) | TYMPADORA1 | |
| SCHEMBL31160244 | 0.84 | TYMP (0.62) | TYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | disclosed |
| US-5525720-A | Synthesis of 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosyl purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |