SCHEMBL8613669

SCHEMBL8613669

CCC(C)c1c(C)c(C)cc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.40
CYP2A6 P11509 3/20 0.40
TSHR P16473 2/20 0.37
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
NR3C1 P04150 1/20 0.34
PGR P06401 1/20 0.34
NR3C2 P08235 1/20 0.34
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
HTR2A P28223 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
TLR8 Q9NR97 1/20 0.32
TLR7 Q9NYK1 1/20 0.32
TYMP P19971 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18949976 0.83 HTR2A (0.42) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL1054281 0.82 CYP1A2 (0.45) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL10634101 0.79 TSHR (0.48) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL19065036 0.77 CYP1A2 (0.44) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL6547602 0.74 TSHR (0.44) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL14665267 0.72 TSHR (0.47) CYP1A2TSHRALDH1A1HSD17B10HPGD
SCHEMBL18350073 0.72 NQO2 (0.41) CYP1A2TSHRALDH1A1HPGDKDM4E
Water SCHEMBL11570775 0.72 IKBKB (0.35) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL6546711 0.72 CYP1A2 (0.47) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL6546616 0.71 TSHR (0.46) CYP1A2CYP2A6TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599448-B1 Solvant for use in carbonless paper, comprising diisopropylmethylnaphthalene, and products utilising same KOCH IND INC (US) 1998-04-29 EP disclosed
US-5489332-A MIXTURE KOCH INDUSTRIES, INC. (US) 1996-02-06 US disclosed
US-5385879-A Carbonless paper solvent comprising diisopropylmethylnaphthalene and products utilizing same KOCH INDUSTRIES, INC. (US) 1995-01-31 US disclosed
EP-0599448-A2 Solvant for use in carbonless paper, comprising diisopropylmethylnaphthalene, and products utilising same KOCH INDUSTRIES, INC. (US) 1994-06-01 EP disclosed