Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574423 | 1.00 | TSHR (0.43) | TSHRNFKB1CYP2C19ESR1CYP3A4 | |
| SCHEMBL14369404 | 0.89 | ESR1 (0.41) | TSHRNFKB1CYP2C19ESR1CYP3A4 | |
| Acetic Acid SCHEMBL11312358 | 0.84 | TSHR (0.38) | TSHRNFKB1CYP2C19ESR1CYP3A4 | |
| SCHEMBL28088669 | 0.81 | TSHR (0.45) | TSHRNFKB1CYP2C19FFAR3 | |
| SCHEMBL16409147 | 0.80 | TSHR (0.41) | TSHRNFKB1CYP2C19 | |
| SCHEMBL9067554 | 0.79 | TSHR (0.48) | TSHRNFKB1CYP2C19FFAR3 | |
| SCHEMBL28448964 | 0.79 | TSHR (0.43) | TSHRNFKB1CYP2C19FFAR3 | |
| SCHEMBL2278363 | 0.77 | TSHR (0.42) | TSHRNFKB1CYP2C19SMN1; SMN2FFAR3 | |
| SCHEMBL8527302 | 0.77 | TSHR (0.42) | TSHRNFKB1CYP2C19FFAR3 | |
| SCHEMBL771854 | 0.77 | TSHR (0.42) | TSHRNFKB1CYP2C19FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876299-A | FOR POLYMERIC LACQUERS | SANDOZ LTD. (CH) | 1989-10-24 | — | — | US | claimed |
| US-7285551-B2 | Fused-ring compounds and use thereof as drugs | JAPAN TOBACCO INC. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-7285551-B2 | Fused-ring compounds and use thereof as drugs | JAPAN TOBACCO INC. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20070231671-A1 | Catalyst Material For Use In Fuel Cell, Catalyst Membrane, Membrane Electrode Assembly and Fuel Cell | FUJIFILM CORPORATION | 2007-10-04 | — | — | US | disclosed |
| US-20070032497-A1 | Fused-ring compounds and use thereof as drugs | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-5728836-A | Process for preparing 4-acylamino-2,2,6,6-tetramethylpiperidines | HUELS AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |
| US-4876299-A | FOR POLYMERIC LACQUERS | SANDOZ LTD. (CH) | 1989-10-24 | — | — | US | disclosed |
| US-3975357-A | SUBSTITUTED PIPERIDINES | SANKYO COMPANY LIMITED (JA) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032497-A1 | Fused-ring compounds and use thereof as drugs | HAVCR2, ZC3HAV1, HLA-C | TSHR 4824/4885NFKB1 1035/4885CYP2C19 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.