Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 10/20 | 0.55 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | HINT1 | P49773 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613718 | 1.00 | TYMP (0.55) | TYMPNT5EHINT1GSK3ARPS6KA3 | |
| SCHEMBL35087 | 0.91 | TYMP (0.54) | TYMPNT5EHINT1GSK3ARPS6KA3 | |
| SCHEMBL8614529 | 0.91 | TYMP (0.53) | TYMPNT5EHINT1PDE2A | |
| SCHEMBL8613382 | 0.90 | TYMP (0.47) | TYMPNT5EPDE2A | |
| SCHEMBL34927 | 0.90 | TYMP (0.64) | TYMPNT5EHINT1GSK3ARPS6KA3 | |
| SCHEMBL34234 | 0.88 | TYMP (0.64) | TYMPNT5EHINT1GSK3ARPS6KA3 | |
| SCHEMBL8612802 | 0.87 | TYMP (0.72) | TYMPNT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL8613729 | 0.85 | TYMP (0.54) | TYMPNT5EPDE2A | |
| SCHEMBL8613736 | 0.85 | TYMP (0.54) | TYMPNT5EPDE2A | |
| SCHEMBL1904550 | 0.84 | TYMP (0.76) | TYMPNT5EHINT1GSK3ARPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750675-A | 2'-\"up\" fluorinated 2'-deoxy-arabinofuranosylpurines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1998-05-12 | — | — | US | claimed |