Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | TACR3 | P29371 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615300 | 0.94 | KMT2A (0.58) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8616412 | 0.88 | TACR3 (0.57) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8617803 | 0.88 | MEN1 (0.52) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8614019 | 0.87 | TACR3 (0.56) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8620889 | 0.87 | HTT (0.61) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8619430 | 0.86 | HTT (0.60) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8616283 | 0.85 | MEN1 (0.50) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8617743 | 0.85 | CYP3A4 (0.65) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8617742 | 0.84 | TACR3 (0.63) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 | |
| SCHEMBL8613178 | 0.84 | MEN1 (0.48) | KMT2AMEN1TACR3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |