SCHEMBL8613982

SCHEMBL8613982

CCN1C(=O)CC(=O)N(CC)S1(=O)=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
F2 P00734 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CTRC Q99895 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12293937 0.71 CA12 (0.32) CA12CA9
SCHEMBL10646550 0.67
SCHEMBL2928083 0.67 F2 (0.38) F2ELANECTSGCTRC
SCHEMBL10611478 0.65 BRD4 (0.31)
SCHEMBL13632829 0.64 BRD4 (0.32) CA12CA9
SCHEMBL141302 0.63 F2 (0.63) F2ELANECTSGCTRC
SCHEMBL26721606 0.63 F2 (0.35) F2ELANECTSGCTRC
Hydrochloric Acid SCHEMBL8590266 0.62 F2 (0.60) F2ELANECTSGCTRC
SCHEMBL21996053 0.62 F2 (0.60) F2ELANECTSGCTRC
SCHEMBL3831786 0.62 F2 (0.60) F2ELANECTSGCTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998051312-A1 THIADIAZINYL CORTICOTROPIN-RELEASING FACTOR BINDING PROTEIN LIGAND INHIBITORS ELI LILLY AND COMPANY (US) 1998-11-19 WO disclosed