⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16261069 | 0.93 | — | — | |
| SCHEMBL12316037 | 0.79 | — | — | |
| SCHEMBL19376915 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL10724194 | 0.75 | — | — | |
| SCHEMBL19634343 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL17383858 | 0.74 | — | — | |
| SCHEMBL5933757 | 0.74 | — | — | |
| SCHEMBL278782 | 0.74 | — | — | |
| SCHEMBL15996556 | 0.72 | — | — | |
| SCHEMBL22048601 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763677-B1 | NOVEL IMIDAZOLE QUINOLINE-BASED IMMUNE SYSTEM MODULATORS | JANUS BIOTHERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-2580210-B1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | SERAGON PHARMACEUTICALS INC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9399735-B2 | Mannich-base inhibitor for decalcification, preparation method and application thereof | PETROCHINA COMPANY LIMITED (CN) | 2016-07-26 | — | — | US | disclosed |
| WO-2015200680-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2015-12-30 | — | — | WO | disclosed |
| US-20150209381-A1 | ON01910.Na ENHANCES CHEMOTHERAPEUTIC AGENT ACTIVITY IN DRUG-RESISTANT TUMORS | THE JOHNS HOPKINS UNIVERSITY | 2015-07-30 | — | — | US | disclosed |
| US-20130256602-A1 | MANNICH-BASE INHIBITOR FOR DECALCIFICATION, PREPARATION METHOD AND APPLICATION THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2013-10-03 | — | — | US | disclosed |
| US-8148552-B2 | Process for the synthesis of anticancer (poly) aminoalkylaminoacetamide derivatives of epipodophyllotoxin | PIERRE FABRE MEDICAMENT (FR) | 2012-04-03 | — | — | US | disclosed |
| US-8143413-B2 | Polycationized phospholipid derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-03-27 | — | — | US | disclosed |
| EP-2316469-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-2316468-A1 | Delivery system and methods for protecting and administering dextroamphetamine | Shire LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-2266590-A2 | Active agent delivery sytems and methods for protecting and administering active agents | Shire LLC (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-2266528-A1 | Process for colouring and/or bleaching human hair using a composition comprising an amino trialkoxysilane or amino trialcenyloxysilane | L'Oréal (FR) | 2010-12-29 | — | — | EP | disclosed |
| US-20100280263-A1 | Process for the Synthesis of Anticancer (Poly) Aminoalkylaminoacetamide Derivatives of Epipodophyllotoxin | PIERRE FABRE MEDICAMENT (FR) | 2010-11-04 | — | — | US | disclosed |
| US-20100094020-A1 | POLYCATIONIZED PHOSPHOLIPID DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |